Chris Lok-To Sham
Dr. (Chris) Lok-To Sham is an Assistant Professor in the Department of Microbiology and Immunology at the National University of Singapore.
He uncovered a widely conserved ATP-binding cassette transporter, FtsEX, that controls peptidoglycan hydrolysis during cytokinesis. During his postdoctoral training, he demonstrated that MurJ is the long-sought transporter of peptidoglycan. Chris started his research group in 2017. His research program aims to elucidate how CPS is produced and how its synthesis is coordinated with assembling other cell envelope layers. Using a multi-disciplinary approach, his research group addressed fundamental questions regarding CPS synthesis and regulation, investigated the role of surface glycan in host-pathogen interactions, and developed innovative techniques to engineer glycans genetically. Chris is the recipient of the National Research Foundation Fellowship, Class of 2019. He is the Vice President of the Singapore Society of Microbiology and Biotechnology and the Research Director of the Infectious Diseases Translational Research Programme at Yong Loo Lin School of Medicine, National University of Singapore.